Quiz

Question :1 All of the following are worrisome features of IPMN except

Enhancing cyst wall
Jaundice
Pancreatitis
Main duct 5-9mm

Question :2 Negative CEA, High amylase & Negative mucin is suggestive of

Pseudocyst pancreas
Serous cystadenoma pancreas
Mucinous cystadenoma pancreas
IPMN

Question :3 Lymph node along splenic artery in carcinoma stomach staging belongs to

10
11
13
15

Question :4 A 43 yr old male patient comes with 5cm thyroid lump involving level 6 lymph nodes. FNAC suggestive of Papillary thyroid carcinoma. TNM staging of patient will be

Stage I
Stage II
Stage III
Stage IV

Question :5 Most common site for Metastases from Malignant Phyllodes is

Bone
Stomach
Lungs
Brain

Question :6 Development of a cutaneous malignancy is associated with chronic exposure to:

Ammonia
Arsenic
Chromium
Benzene

Question :7 Most common malignant neoplasm in Li Fraumeni syndrome is

Soft tissue sarcoma
Breast cancers
Brain tumors
Adrenocortical carcinoma

Question :8 In Masoaka staging of Thymoma, Stage 1 is

Macroscopically completely encapsulated and microscopic no capsular invasion
Macroscopic invasion into mediastinal pleura
Macroscopic invasion into Pericardium, Great vessels & Lung
Pleural dissemination

Question :9 Choriocarcinoma confined to Uterus. Stage is

I
II
III
IV

Question :10 Diarrhea in Medullary thyroid carcinoma is due to

5 hydroxytryptamine
Prostaglandins
Calcitonin
Both A & B

Question :11 Guidelines for EMR in Early gastric cancer include all except

Tumor limited to mucosa
No ulceration
Tumor smaller than 3cm
No lymphovascular invasion

Question :12 Primary reconstructive flap of choice in Dentate mandible with Oral cancer

Iliac crest
Fibula
Composite flap
PMMF

Question :13 Risk of Malignancy in type 3 Bosnaik renal cysts is

0%
5%
50%
100%

Question :14 All are true about HNPCC Except

Most common genes affected are MLH1 & MSH2
Life time risk of developing Colorectal cancer is 80%
Most cancers develop in distal colon
Females have 30-50% chances of developing Endometrial cancer

Question :15 Tumor deposits in mesentery in Carcinoma colon as per AJCC staging is

N1a
N1a
N2c
M1

Question :16 Which of the following are not an indication of MRI in women at high risk breast cancer

With a known BRCA mutation
Who have a first-degree relative with a BRCA mutation
Who had been treated with radiation to the chest
Who have an approximately 10% to 15% or greater lifetime risk of breast cancer

Question :17 Characteristics of Ideal tumor markers include all Except

Should be expressed exclusively by particular tumor
Collection of specimen for tumor marker assay should be easy
Assay itself should be reproducible
It should be Rapid & Expensive

Question :18 Not a nuclear microscopic feature of malignancy is

Enlargement
Pleomorphism
Hypochromaticity
Chromatin clumping

Question :19 Most common presentation of Nasopharyngeal carcinoma is

Hearing loss
Trotter’s triad
Blood stained nasal discharge
Cervical lymphadenopathy

Question :20 Siewert classification is for classifying

Lung cancers
Adrenal carcinoma
Gastroesophageal Junctional tumours
Neuroendocrine tumours

Question :21 True about Spermatocytic seminoma is

Seen generally in older men
Express placental alkaline phosphatase
Metastatic potential is high
Secretes high amount of AFP

Question :22 Which is true regarding paget’s disease of breast

Accounts for about 1% of all breast malignancies
Best treated by radiation therapy
Classified as T4 disease as per TNM Staging
Risk of lymph node metastasis is 30%

Question :23 More than ___% of cancers of uterine cervix are associated with HPV

50%
90%
75%
40%

Question :24 Pectoralis major myocutaneous flap is based on the:

Lateral thoracic artery
Perforating branch of thoracoabdominal artery
Dorsal scapular artery
Perforating branches of internal mammary artery

Question :25 Li-Fraumeni syndrome is associated with germ line mutations in:

Cyclin D1
ATM
BRCA 1
p53

Question :26 Germline mutation of which tumour suppressor gene is most frequently associated with hereditary pancreatic cancer?

BRCA 2
PALB 2
K ras
P 53

Question :27 On immunohistochemistry, malignant mesothelioma is +ve for:

Calretinin
Ber-EP4
Moc-31
TTF-1

Question :28 Most common genetic mutation in Nevoid basal cell carcinoma syndrome is:

PTCH
STK11
TSC
RECQL4

Question :29 AMICO CRITERIA for risk categorization in prostatic cancer includes all except:

Blood PSA level
Gleason grade
T stage
PSA velocity

Question :30 Most common 1st metastatic site for ocular melanoma:

Liver
Skin
Brain
Lung

Question :31 Which of the following factors is not considered when considering patient for Genetic counseling for risk assessment of Familial Breast or Ovarian cancer

Breast cancer younger than 40 yrs age
Family member with male breast cancer
Bilateral breast cancer
Low grade papillary serous carcinoma of Ovary

Question :32 Which of the following statements is not true?

In hyperfractionation dose per fraction is reduced
In accelerated fractionation, Total dose is reduced
In hypofractionation, dose per fraction is Increased
In hyperfractionation, Total dose is reduced

Question :33 Which of the following is not a radiosensitizer?

Metronidazole
Cisplatin
GM CSF
Hydroxyurea

Question :34 Which of the following is not a Contraindication to Radiotherapy in Gynecological cancers?

Uterovaginal prolapse
Severe Anemia
Severe Anemia
Diabetes

Question :35 Which of the following is not included in High risk factors for Endometrial cancers

Late menopause
Nulliparity
Multiparity
Obesity

Question :36 Which of the following is not a Tumor Associated Antigens?

MUC1
CEA
BRCA 2
HER 2/NEU

Question :37 Which of the following is not true about Leiomyosaroma?

More common in African Americans
Median age at diagnosis is Early 50s
Usually present as stage IV disease
Vascular invasion & extrauterine tumor spread are associated with worse prognosis

Question :38 Short latency aggressive papillary carcinoma thyroid is associated with which of the following Oncogene?

RET/PTC 1
RET/PTC 2
RET/PTC 3
RET/PTC 4

Question :39 Syndromes associated with hereditary breast cancer are all Except

Lifraumeni syndrome
Peutz jeghers syndrome
Cowden disease
Cronkhite Canada syndrome

Question :40 Which of the following is not an Ectodermal manifestations of FAP

Desmoid tumor
Pilomatrixoma
CHRPE
Epidermoid cyst

Question :41 According to Hayflick hypothesis maximum no. of divisions for normal human cells is

10-20
20-40
40-60
60-80

Question :42 A tumor of 1cm diameter will contain ____cells

103
106
109
1012

Question :43 Indications for Post op Radiotherapy in Head & Neck cancer include all Except

Close or +ve margins
Extracapsular extension
N2a or greater cervical node
T1or T2 tumor

Question :44 Renal cell carcinoma with poor prognosis is

Clear cell carcinoma
Papillary carcinoma
Chromophobe carcinoma
Collecting duct carcinoma

Question :45 Strongest predisposing factor for Basal cell carcinoma is

Ionizing radiation
UV radiation
Genetic skin cancer syndromes
Arsenical compounds

Question :46 What percentage of cases have metastasis in Cutaneous Squamous cell carcinoma?

2%
10%
50%
80%

Question :47 All are true about Carcinoma Breast in pregnancy except

Radiotherapy is avoided
Chemotherapy is avoided in 1st trimester
Most tumors are Hormone receptor +ve
All the above are true

Question :48 Tumor size over which size should be considered to have metastatic potential in GIST?

3 cm
5 cm
7 cm
10 cm

Question :49 Which of the following is incorrect about APBI (Accelerated partial breast irradiation)?

APBI is delivered in an abbreviated fashion & lower total dose than standard course of whole breast radiation
Suitable patients include women of 60 or more
Suitable patients include those with tumor margins 2mm or greater
Suitable patients include those with multifocal disease

Question :50 A 25-year-old male presented with painless testicular swelling and with history of fever and weight loss. All the following investigations are indicated in this patient except:

USG scrotum
CT abdomen and pelvis
Chest X-ray
Transscrotal biopsy

Question :51 Carcinoma breast is diagnosed in 2nd trimester of pregnancy.Which should n’t be done?

Breast conservation surgery/BCS
Chemotherapy
Modified radical mastectomy
30 focal radiotherapy to local area

Question :52 A patient is diagnosed with Liposarcoma of 8x6x4 em involving the posterior part of thigh. Treatment of choice in this patient is:

Above thigh amputation
Extra compartmental excision
Chemotherapy
Wide local excision

Question :53 A 45 years old male having multiple sexual partners presents with lesion in the anus. Biopsy reveals early stage of squamous cell carcinoma of anus. Correct management for this patient is:

Wide local excision
Wide local excision
Chemoradiation nigro regimen
Antiviral therapy

Question :54 A 47-year-old patient presents with a slowly enlarging right parotid mass. You are suspicious for neoplastic process and perform a FNAC. Which of the following is true about parotid neoplasms?

Approximately 75%–80% of parotid gland tumors are malignant
Most common parotid tumor is mucoepidermoid carcinoma
Pleomorphic adenoma is seen bilaterally in 50% of patients
Smoking is an etiologic risk factor for warthin’s tumor

Question :55 Which of the following abnormalities is both paraneoplastic syndrome associated with HCC, and may also be caused by end-stage liver failure?

Hypoglycemia
Erythrocytosis
Hypercalcemia
Hypercholesterolemia

Question :56 Seed soil theory is given by

Ehrlich
Kocher
Paget
Halsted

Question :57 Which of the following Anticancer drug causes Hemolytic uremic syndrome

Cyclophosphamide
Mitomycin C
Cisplatin
Hydroxyurea

Question :58 Death in esophageal cancer usually occurs due to

Metastasis
Cardiac complications
Anastomotic leak
Tracheoesophageal fistula

Question :59 WDHA syndrome seen in

Insulinoma
VIPoma
Gastrinoma
GLucagonoma

Question :60 Which of the following is not considered a high risk condition for Oral cavity Cancer?

Erythroplakia
Speckled Erythroplakia
Discoid lupus erythematosus
Chronic hyperplastic candidiasis